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HomoloGene:20802. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PPFIA1,  H.sapiens
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
NP_003617.1
1202 aa
PPFIA1,  P.troglodytes
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
XP_003952009.1
1255 aa
PPFIA1,  C.lupus
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
XP_005631430.1
1267 aa
PPFIA1,  B.taurus
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
NP_001178306.1
1202 aa
Ppfia1,  M.musculus
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
NP_001182015.1
1266 aa
Ppfia1,  R.norvegicus
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
NP_001099790.2
1190 aa
PPFIA1,  G.gallus
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
XP_421074.4
1250 aa
ppfia1,  X.tropicalis
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
NP_001121469.1
1211 aa
zgc:171298,  D.rerio
zgc:171298
NP_001104714.1
1194 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Liprin-α is involved in exocytosis and cell spreading in mast cells.
Nomura H, et al. Immunol Lett 139, 110-6 (2011).
Identification and characterization of mouse Ppfia1 gene in silico.
Katoh M & Katoh M. Int J Mol Med 12, 263-7 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PspA (COG1842)
  Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].
CDC37_N (cl03951)
  Cdc37 N terminal kinase binding.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
SAM_superfamily (cl15755)
  SAM (Sterile alpha motif ).
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ppfia1 includes H.sapiens PPFIA1 and R.norvegicus Ppfia1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 9 species)
Actinopterygii - bony fishes (11 transcripts, 5 species)
Amniota - vertebrates (2 transcripts, 1 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (6 transcripts, 6 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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