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HomoloGene:39963. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

VTI1A,  H.sapiens
vesicle transport through interaction with t-SNAREs 1A
NP_660207.2
217 aa
VTI1A,  P.troglodytes
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
XP_003951807.1
224 aa
VTI1A,  C.lupus
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
XP_005637790.1
224 aa
VTI1A,  B.taurus
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
NP_001073260.1
117 aa
Vti1a,  M.musculus
vesicle transport through interaction with t-SNAREs 1A
NP_058558.1
217 aa
Vti1a,  R.norvegicus
vesicle transport through interaction with t-SNAREs 1A
NP_075589.1
217 aa
VTI1A,  G.gallus
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
NP_001264329.1
224 aa
vti1a,  X.tropicalis
vesicle transport through interaction with t-SNAREs 1A
NP_001072230.1
187 aa
vti1a,  D.rerio
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
NP_001030152.1
191 aa
Vti1,  D.melanogaster
Vti1
NP_612053.1
230 aa
AgaP_AGAP009322,  A.gambiae
AgaP_AGAP009322
XP_309991.2
216 aa
vti-1,  C.elegans
vti-1
NP_502781.1
224 aa
AGOS_AFL168W,  E.gossypii
AGOS_AFL168W
NP_985382.1
215 aa
vti1,  S.pombe
vti1
NP_596668.1
214 aa
MGG_01124,  M.oryzae
MGG_01124
XP_003717810.1
233 aa
NCU05959,  N.crassa
NCU05959
XP_958573.1
228 aa
SGR4,  A.thaliana
SGR4
NP_198767.1
221 aa
VTI13,  A.thaliana
VTI13
NP_189554.2
195 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Epsin N-terminal homology domains bind on opposite sides of two SNAREs.
Wang J, et al. Proc Natl Acad Sci U S A 108, 12277-82 (2011).
Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis.
Sanmartín M, et al. Proc Natl Acad Sci U S A 104, 3645-50 (2007).
The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners.
Kreykenbohm V, et al. Eur J Cell Biol 81, 273-80 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
V-SNARE_C (pfam12352)
  Snare region anchored in the vesicle membrane C-terminus.
V-SNARE (pfam05008)
  Vesicle transport v-SNARE protein N-terminus.
V-SNARE (pfam05008)
  Vesicle transport v-SNARE protein N-terminus.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vti1a includes H.sapiens VTI1A and R.norvegicus Vti1a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (91 transcripts, 33 species)
Liliopsida - monocots (21 transcripts, 9 species)
Coniferopsida - conifers (6 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Mammalia - mammals (11 transcripts, 8 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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