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HomoloGene:100939. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ACSL6,  H.sapiens
acyl-CoA synthetase long-chain family member 6
NP_001009185.1
722 aa
ACSL6,  P.troglodytes
acyl-CoA synthetase long-chain family member 6
XP_003310893.2
688 aa
ACSL6,  C.lupus
acyl-CoA synthetase long-chain family member 6
XP_005626563.1
722 aa
ACSL6,  B.taurus
acyl-CoA synthetase long-chain family member 6
NP_001033131.1
697 aa
Acsl6,  M.musculus
acyl-CoA synthetase long-chain family member 6
NP_001028770.1
697 aa
Acsl6,  R.norvegicus
acyl-CoA synthetase long-chain family member 6
NP_570095.1
697 aa
ACSL6,  G.gallus
acyl-CoA synthetase long-chain family member 6
XP_414641.4
723 aa
acsl6,  X.tropicalis
acyl-CoA synthetase long-chain family member 6
NP_001072330.1
698 aa
acsl1b,  D.rerio
acyl-CoA synthetase long-chain family member 1b
NP_001003569.1
697 aa
acsl1a,  D.rerio
acyl-CoA synthetase long-chain family member 1a
NP_001027007.1
697 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Myelodysplastic syndrome.
Myelogenous leukemia, acute.



Publications
Articles associated with genes and sequences of this homology group.

Transient maintenance in bioreactor improves health of neuronal cells.
Di Loreto S, et al. In Vitro Cell Dev Biol Anim 42, 134-42 (2006).
Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism.
Marszalek JR, et al. J Biol Chem 280, 10817-26 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLN02736 (PLN02736)
  long-chain acyl-CoA synthetase.
AFD_class_I (cl17068)
  Adenylate forming domain, Class I.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Acsl6 includes H.sapiens ACSL6 and R.norvegicus Acsl6.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (18 transcripts, 9 species)
Mammalia - mammals (14 transcripts, 14 species)
Ascidiacea - tunicates (6 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Liliopsida - monocots (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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