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HomoloGene:23168. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IKBKE,  H.sapiens
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NP_054721.1
716 aa
IKBKE,  M.mulatta
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
XP_001088252.1
716 aa
IKBKE,  C.lupus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
XP_536108.3
659 aa
IKBKE,  B.taurus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NP_001039810.1
718 aa
Ikbke,  M.musculus
inhibitor of kappaB kinase epsilon
NP_062751.2
717 aa
Ikbke,  R.norvegicus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NP_001102324.1
717 aa
IKBKE,  G.gallus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
XP_004935017.1
805 aa
ikbke,  X.tropicalis
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
XP_002940557.2
693 aa
ikbke,  D.rerio
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NP_001002751.1
721 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis.
Wang Y, et al. Proc Natl Acad Sci U S A 110, 11139-44 (2013).
IKK-ε coordinates invasion and metastasis of ovarian cancer.
Hsu S, et al. Cancer Res 72, 5494-504 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
UBL_TBK1_like (cd12219)
  Ubiquitin-Like Domain Of Human Tbk1 and similar proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ikbke includes H.sapiens IKBKE and R.norvegicus Ikbke.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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