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HomoloGene:8560. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CD274,  H.sapiens
CD274 molecule
NP_054862.1
290 aa
CD274,  P.troglodytes
CD274 molecule
XP_001140705.1
290 aa
CD274,  M.mulatta
CD274 molecule
NP_001077358.1
290 aa
CD274,  C.lupus
CD274 molecule
XP_005615991.1
289 aa
CD274,  B.taurus
CD274 molecule
NP_001156884.1
289 aa
Cd274,  M.musculus
CD274 antigen
NP_068693.1
290 aa
Cd274,  R.norvegicus
CD274 molecule
NP_001178883.1
290 aa
CD274,  G.gallus
CD274 molecule
XP_424811.4
471 aa
cd274,  X.tropicalis
CD274 molecule
XP_004911464.1
277 aa
si:ch211-241b2.5,  D.rerio
si:ch211-241b2.5
XP_003200855.2
760 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PD-L1 limits the mucosal CD8+ T cell response to Chlamydia trachomatis.
Fankhauser SC & Starnbach MN. J Immunol 192, 1079-90 (2014).
Programmed death ligand-1 expression in non-small cell lung cancer.
Velcheti V, et al. Lab Invest 94, 107-16 (2014).
Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway.
Charles R, et al. Transplantation 96, 17-24 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IG (smart00409)
  Immunoglobulin.
IG_like (smart00410)
  Immunoglobulin like.
V-set (pfam07686)
  Immunoglobulin V-set domain.
Ig (cl11960)
  Immunoglobulin domain.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cd274 includes H.sapiens CD274 and R.norvegicus Cd274.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)

 

 

 

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