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HomoloGene:4181. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ACTR2,  H.sapiens
ARP2 actin-related protein 2 homolog (yeast)
NP_001005386.1
399 aa
ACTR2,  P.troglodytes
ARP2 actin-related protein 2 homolog (yeast)
XP_001155450.3
449 aa
ACTR2,  M.mulatta
ARP2 actin-related protein 2 homolog (yeast)
XP_001090768.2
394 aa
ACTR2,  C.lupus
ARP2 actin-related protein 2 homolog (yeast)
XP_852707.1
399 aa
ACTR2,  B.taurus
ARP2 actin-related protein 2 homolog (yeast)
NP_001095683.1
394 aa
Actr2,  M.musculus
ARP2 actin-related protein 2
NP_666355.1
394 aa
Actr2,  R.norvegicus
ARP2 actin-related protein 2 homolog (yeast)
NP_001009268.1
394 aa
ACTR2,  G.gallus
ARP2 actin-related protein 2 homolog (yeast)
NP_990555.1
394 aa
actr2,  X.tropicalis
ARP2 actin-related protein 2 homolog
NP_001025569.1
394 aa
actr2a,  D.rerio
ARP2 actin-related protein 2a homolog (yeast)
NP_998664.1
394 aa
actr2b,  D.rerio
ARP2 actin-related protein 2b homolog (yeast)
NP_001017542.1
394 aa
Arp2,  D.melanogaster
Actin-related protein 2
NP_001259621.1
399 aa
AgaP_AGAP000985,  A.gambiae
AgaP_AGAP000985
XP_309181.5
395 aa
arx-2,  C.elegans
arx-2
NP_505657.1
395 aa
ARP2,  S.cerevisiae
ARP2
NP_010255.1
391 aa
KLLA0C03850g,  K.lactis
KLLA0C03850g
XP_452368.1
391 aa
AGOS_ADR316W,  E.gossypii
AGOS_ADR316W
NP_984412.1
391 aa
arp2,  S.pombe
arp2
XP_001713111.1
390 aa
MGG_17001,  M.oryzae
MGG_17001
XP_003715887.1
398 aa
NCU07171,  N.crassa
NCU07171
XP_957396.1
395 aa
ARP2,  A.thaliana
ARP2
NP_189336.1
389 aa
Os08g0369300,  O.sativa
Os08g0369300
NP_001061655.2
441 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Arp2/3 is a negative regulator of growth cone translocation.
Strasser GA, et al. Neuron 43, 81-94 (2004).
Actin-related protein (Arp2) inserts into artificial lipid membranes.
Goldmann WH & Isenberg G. Cell Biol Int 26, 1073-8 (2002).
Purification of Arp2/3 complex from Saccharomyces cerevisiae.
Doolittle LK, et al. Methods Mol Biol 1046, 251-71 (2013).
Molecular analysis of Arp2/3 complex activation in cells.
Galletta BJ, et al. Biophys J 103, 2145-56 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NBD_sugar-kinase_HSP70_actin (cl17037)
  Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Actr2 includes H.sapiens ACTR2 and R.norvegicus Actr2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (28 transcripts, 10 species)
Mammalia - mammals (18 transcripts, 14 species)
Ascidiacea - tunicates (7 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 10 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (6 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (4 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (30 transcripts, 22 species)
Liliopsida - monocots (13 transcripts, 9 species)
Coniferopsida - conifers (4 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (4 transcripts, 2 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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