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HomoloGene:7596. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC27A5,  H.sapiens
solute carrier family 27 (fatty acid transporter), member 5
NP_036386.1
690 aa
SLC27A5,  P.troglodytes
solute carrier family 27 (fatty acid transporter), member 5
XP_001148729.1
690 aa
LOC713713,  M.mulatta
bile acyl-CoA synthetase-like
XP_001103163.2
587 aa
SLC27A5,  B.taurus
solute carrier family 27 (fatty acid transporter), member 5
NP_001096743.1
690 aa
Slc27a5,  M.musculus
solute carrier family 27 (fatty acid transporter), member 5
NP_033538.2
689 aa
Slc27a5,  R.norvegicus
solute carrier family 27 (fatty acid transporter), member 5
NP_077057.1
690 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency.
Setchell KD, et al. Gastroenterology 144, 945-955.e6; quiz e14-5 (2013).
Bile acid-CoA ligase deficiency--a new inborn error of bile acid metabolism.
Chong CP, et al. J Inherit Metab Dis 35, 521-30 (2012).
Molecular cloning and expression of rat liver bile acid CoA ligase.
Falany CN, et al. J Lipid Res 43, 2062-71 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PRK08279 (PRK08279)
  long-chain-acyl-CoA synthetase; Validated.
AFD_class_I (cl17068)
  Adenylate forming domain, Class I.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc27a5 includes H.sapiens SLC27A5 and R.norvegicus Slc27a5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)

 

 

 

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