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HomoloGene:3074. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SHMT1,  H.sapiens
serine hydroxymethyltransferase 1 (soluble)
NP_004160.3
483 aa
SHMT1,  P.troglodytes
serine hydroxymethyltransferase 1 (soluble)
XP_001157513.1
483 aa
SHMT1,  M.mulatta
serine hydroxymethyltransferase 1 (soluble)
XP_001096314.1
483 aa
SHMT1,  C.lupus
serine hydroxymethyltransferase 1 (soluble)
XP_005620199.1
484 aa
SHMT1,  B.taurus
serine hydroxymethyltransferase 1 (soluble)
NP_001015553.1
484 aa
Shmt1,  M.musculus
serine hydroxymethyltransferase 1 (soluble)
NP_033197.2
478 aa
Shmt1,  R.norvegicus
serine hydroxymethyltransferase 1 (soluble)
NP_001041307.1
681 aa
SHMT1,  G.gallus
serine hydroxymethyltransferase 1 (soluble)
XP_004945260.1
639 aa
shmt1,  X.tropicalis
serine hydroxymethyltransferase 1 (soluble)
NP_001015914.1
485 aa
shmt1,  D.rerio
serine hydroxymethyltransferase 1 (soluble)
NP_957340.1
481 aa
CG3011,  D.melanogaster
CG3011
NP_572278.1
537 aa
AgaP_AGAP001065,  A.gambiae
AgaP_AGAP001065
XP_003437197.1
467 aa
mel-32,  C.elegans
mel-32
NP_741197.1
507 aa
SHM2,  S.cerevisiae
SHM2
NP_013159.1
469 aa
KLLA0F08921g,  K.lactis
KLLA0F08921g
XP_455485.1
469 aa
AGOS_ACR215C,  E.gossypii
AGOS_ACR215C
NP_983617.2
469 aa
SPAC24C9.12c,  S.pombe
SPAC24C9.12c
NP_594037.1
467 aa
MGG_00923,  M.oryzae
MGG_00923
XP_003718036.1
482 aa
NCU02274,  N.crassa
NCU02274
XP_959918.1
480 aa
SHM2,  A.thaliana
SHM2
NP_568488.2
533 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAT_I (cl18945)
  Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Shmt1 includes H.sapiens SHMT1 and R.norvegicus Shmt1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (119 transcripts, 33 species)
Coniferopsida - conifers (15 transcripts, 3 species)
Liliopsida - monocots (12 transcripts, 9 species)
Bryopsida - mosses (4 transcripts, 1 species)
Isoetopsida - club-mosses (3 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (4 transcripts, 2 species)

Chordata
Mammalia - mammals (16 transcripts, 12 species)
Actinopterygii - bony fishes (14 transcripts, 10 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 12 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (4 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (3 transcripts, 2 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

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