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HomoloGene:40661. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SUPT6H,  H.sapiens
suppressor of Ty 6 homolog (S. cerevisiae)
NP_003161.2
1726 aa
SUPT6H,  P.troglodytes
suppressor of Ty 6 homolog (S. cerevisiae)
XP_001143115.2
1726 aa
SUPT6H,  M.mulatta
suppressor of Ty 6 homolog (S. cerevisiae)
XP_001106850.2
1670 aa
SUPT6H,  C.lupus
suppressor of Ty 6 homolog (S. cerevisiae)
XP_537747.2
1726 aa
SUPT6H,  B.taurus
suppressor of Ty 6 homolog (S. cerevisiae)
NP_001180055.1
1726 aa
Supt6,  M.musculus
suppressor of Ty 6
NP_033323.2
1726 aa
Supt6h,  R.norvegicus
suppressor of Ty 6 homolog (S. cerevisiae)
NP_001178749.1
1726 aa
SUPT6H,  G.gallus
suppressor of Ty 6 homolog (S. cerevisiae)
XP_423183.3
1726 aa
supt6h,  X.tropicalis
suppressor of Ty 6 homolog
NP_001072665.1
519 aa
supt6h,  D.rerio
suppressor of Ty 6 homolog
NP_660094.1
1726 aa
Spt6,  D.melanogaster
Spt6
NP_651962.2
1831 aa
AgaP_AGAP003619,  A.gambiae
AgaP_AGAP003619
XP_313379.5
1865 aa
emb-5,  C.elegans
emb-5
NP_497969.1
1521 aa
SPT6,  S.cerevisiae
SPT6
NP_011631.1
1451 aa
KLLA0B11385g,  K.lactis
KLLA0B11385g
XP_452036.1
1460 aa
AGOS_AAR031W,  E.gossypii
AGOS_AAR031W
NP_982572.2
1432 aa
spt6,  S.pombe
spt6
NP_594487.2
1365 aa
MGG_11491,  M.oryzae
MGG_11491
XP_003718184.1
1407 aa
NCU04611,  N.crassa
NCU04611
XP_958854.1
1407 aa
GTB1,  A.thaliana
GTB1
NP_001077775.1
1642 aa
AT1G63210,  A.thaliana
AT1G63210
NP_176510.1
1197 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Structure and in vivo requirement of the yeast Spt6 SH2 domain.
Dengl S, et al. J Mol Biol 389, 211-25 (2009).
Mutations affecting neural survival in the zebrafish Danio rerio.
Abdelilah S, et al. Development 123, 217-27 (1996).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tex_N (pfam09371)
  Tex-like protein N-terminal domain.
HHH_3 (pfam12836)
  Helix-hairpin-helix motif.
RuvC_resolvase (cl00243)
  Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes ...
Tex_N (pfam09371)
  Tex-like protein N-terminal domain.
SPT6_acidic (pfam14632)
  Acidic N-terminal SPT6.
HTH_44 (pfam14641)
  Helix-turn-helix DNA-binding domain of SPT6.
DLD (pfam14878)
  Death-like domain of SPT6.
S1_like (cl09927)
  S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. ...
SH2 (cl15255)
  Src homology 2 (SH2) domain.
UPF0081 (cl17278)
  Uncharacterized protein family (UPF0081).
ENDO3c (cl19066)
  endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Supt6 includes H.sapiens SUPT6H.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (26 transcripts, 9 species)
Mammalia - mammals (12 transcripts, 11 species)
Amphibia - amphibians (5 transcripts, 2 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (18 transcripts, 17 species)
Liliopsida - monocots (4 transcripts, 4 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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