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HomoloGene:9453. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CNOT1,  H.sapiens
CCR4-NOT transcription complex, subunit 1
NP_057368.3
2376 aa
CNOT1,  P.troglodytes
CCR4-NOT transcription complex, subunit 1
XP_511007.2
2376 aa
CNOT1,  M.mulatta
CCR4-NOT transcription complex, subunit 1
XP_001102008.2
2340 aa
CNOT1,  C.lupus
CCR4-NOT transcription complex, subunit 1
XP_535279.4
2376 aa
CNOT1,  B.taurus
CCR4-NOT transcription complex, subunit 1
NP_001192968.1
2376 aa
Cnot1,  M.musculus
CCR4-NOT transcription complex, subunit 1
NP_835179.1
2371 aa
Cnot1,  R.norvegicus
CCR4-NOT transcription complex, subunit 1
NP_001128312.1
2376 aa
CNOT1,  G.gallus
CCR4-NOT transcription complex subunit 1-like
NP_001264062.1
2376 aa
cnot1,  X.tropicalis
CCR4-NOT transcription complex, subunit 1
NP_001090658.1
2388 aa
cnot1,  D.rerio
CCR4-NOT transcription complex, subunit 1
NP_001073420.1
2374 aa
Not1,  D.melanogaster
Not1
NP_724798.3
2505 aa
AgaP_AGAP009057,  A.gambiae
AgaP_AGAP009057
XP_319808.4
2198 aa
let-711,  C.elegans
let-711
NP_498516.2
2527 aa
AT1G02080,  A.thaliana
AT1G02080
NP_171710.4
2431 aa
Os10g0556801,  O.sativa
Os10g0556801
NP_001176268.1
2400 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Gastrulation and homeobox genes in chick embryos.
Lemaire L & Kessel M. Mech Dev 67, 3-16 (1997).
Structure and assembly of the NOT module of the human CCR4-NOT complex.
Boland A, et al. Nat Struct Mol Biol 20, 1289-97 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Not1 (pfam04054)
  CCR4-Not complex component, Not1.
DUF3819 (pfam12842)
  Domain of unknown function (DUF3819).
Not1 (pfam04054)
  CCR4-Not complex component, Not1.
DUF3819 (pfam12842)
  Domain of unknown function (DUF3819).
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cnot1 includes H.sapiens CNOT1 and R.norvegicus RGD1308009.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (27 transcripts, 16 species)
Actinopterygii - bony fishes (18 transcripts, 8 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (4 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (5 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (40 transcripts, 26 species)
Liliopsida - monocots (19 transcripts, 9 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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