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HomoloGene:7242. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BAX,  H.sapiens
BCL2-associated X protein
NP_620116.1
192 aa
BAX,  P.troglodytes
BCL2-associated X protein
XP_001155879.2
192 aa
BAX,  M.mulatta
BCL2-associated X protein
XP_001112353.1
192 aa
BAX,  C.lupus
BCL2-associated X protein
NP_001003011.1
192 aa
BAX,  B.taurus
BCL2-associated X protein
NP_776319.1
192 aa
Bax,  M.musculus
BCL2-associated X protein
NP_031553.1
192 aa
Bax,  R.norvegicus
Bcl2-associated X protein
NP_058755.2
192 aa
bax,  X.tropicalis
BCL2-associated X protein
NP_989185.1
221 aa
baxa,  D.rerio
bcl2-associated X protein, a
NP_571637.1
192 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Colorectal cancer.
T-cell acute lymphoblastic leukemia.



Publications
Articles associated with genes and sequences of this homology group.

Enhanced odor discrimination learning in aged Bax-KO mice.
Kim WR & Sun W. Neurosci Lett 548, 196-200 (2013).
Non-canonical function of Bax in stress-induced nuclear protein redistribution.
Lindenboim L, et al. Cell Mol Life Sci 70, 3013-27 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
bcl-2 (TIGR00865)
  apoptosis regulator.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bax includes H.sapiens BAX and R.norvegicus Bax.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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