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HomoloGene:4314. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SMAD7,  H.sapiens
SMAD family member 7
NP_005895.1
426 aa
SMAD7,  P.troglodytes
SMAD family member 7
XP_512124.2
426 aa
SMAD7,  C.lupus
SMAD family member 7
XP_850493.2
431 aa
SMAD7,  B.taurus
SMAD family member 7
NP_001179794.1
430 aa
Smad7,  M.musculus
SMAD family member 7
NP_001036125.1
426 aa
Smad7,  R.norvegicus
SMAD family member 7
NP_110485.1
426 aa
SMAD7,  G.gallus
SMAD family member 7
XP_427238.2
388 aa
SMAD7B,  G.gallus
TGF-beta signal pathway antagonist Smad7
NP_001153135.1
388 aa
smad7,  X.tropicalis
SMAD family member 7
XP_002936553.2
382 aa
smad7,  D.rerio
MAD, mothers against decapentaplegic homolog 7 (Drosophila)
NP_778257.2
372 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Colorectal cancer, susceptiblity to.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
MH2 (cl00056)
  C-terminal Mad Homology 2 (MH2) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Smad7 includes H.sapiens SMAD7 and R.norvegicus Smad7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (10 transcripts, 8 species)
Mammalia - mammals (9 transcripts, 9 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

 

 

 

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