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HomoloGene:1510. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

F2R,  H.sapiens
coagulation factor II (thrombin) receptor
NP_001983.2
425 aa
F2R,  P.troglodytes
coagulation factor II (thrombin) receptor
XP_526888.3
425 aa
F2R,  M.mulatta
coagulation factor II (thrombin) receptor
XP_001106136.1
425 aa
F2R,  C.lupus
coagulation factor II (thrombin) receptor
XP_005618243.1
401 aa
F2R,  B.taurus
coagulation factor II (thrombin) receptor
NP_001096567.1
427 aa
F2r,  M.musculus
coagulation factor II (thrombin) receptor
NP_034299.2
430 aa
F2r,  R.norvegicus
coagulation factor II (thrombin) receptor
NP_037082.2
432 aa
F2R,  G.gallus
coagulation factor II (thrombin) receptor
XP_004937394.1
441 aa
f2r,  X.tropicalis
coagulation factor II (thrombin) receptor
XP_004910450.1
416 aa
f2r,  D.rerio
coagulation factor II (thrombin) receptor
NP_001108318.1
413 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Protease activated receptor-1 and brain edema formation in glioma models.
Xie Q, et al. Acta Neurochir Suppl 118, 191-4 (2013).
PAR-1 contributes to the innate immune response during viral infection.
Antoniak S, et al. J Clin Invest 123, 1310-22 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus F2r includes H.sapiens F2R and R.norvegicus F2r.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

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