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HomoloGene:1371. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CENPC,  H.sapiens
centromere protein C
NP_001803.2
943 aa
CENPC1,  P.troglodytes
centromere protein C 1
XP_001164757.1
943 aa
CENPC1,  M.mulatta
centromere protein C 1
XP_001099283.2
945 aa
CENPC,  C.lupus
centromere protein C
XP_005628312.1
941 aa
CENPC1,  B.taurus
centromere protein C 1
NP_001039346.2
944 aa
Cenpc1,  M.musculus
centromere protein C1
NP_031709.2
906 aa
Cenpc,  R.norvegicus
centromere protein C
NP_001004098.1
916 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Efficient conditional mutation of the vertebrate CENP-C gene.
Fukagawa T & Brown WR. Hum Mol Genet 6, 2301-8 (1997).
FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21.
Xie Y & Heng HH. Cytogenet Cell Genet 74, 192-3 (1996).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Mif2 (pfam11699)
  Mif2/CENP-C like.
CENP-C_C (pfam11699)
  Mif2/CENP-C like.
CENP_C_N (pfam15622)
  Kinetochore assembly subunit CENP-C N-terminal.
CENP-C_mid (pfam15620)
  Centromere assembly component CENP-C middle DNMT3B-binding region.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cenpc1 includes H.sapiens CENPC1 and R.norvegicus Cenpc1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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