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HomoloGene:7254. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CASP2,  H.sapiens
caspase 2, apoptosis-related cysteine peptidase
NP_116764.2
452 aa
CASP2,  P.troglodytes
caspase 2, apoptosis-related cysteine peptidase
XP_519448.2
452 aa
CASP2,  C.lupus
caspase 2, apoptosis-related cysteine peptidase
NP_001182080.1
452 aa
CASP2,  B.taurus
caspase 2, apoptosis-related cysteine peptidase
NP_001137576.1
452 aa
Casp2,  M.musculus
caspase 2
NP_031636.1
452 aa
Casp2,  R.norvegicus
caspase 2
NP_071967.2
452 aa
CASP2,  G.gallus
caspase 2, apoptosis-related cysteine peptidase
NP_001161173.1
424 aa
LOC100486813,  X.tropicalis
caspase-2-like
XP_002941266.2
420 aa
casp2,  D.rerio
caspase 2, apoptosis-related cysteine protease
NP_001036160.1
435 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CARD_CASP2 (cd08332)
  Caspase activation and recruitment domain of Caspase-2.
DD_superfamily (cl14633)
  The Death Domain Superfamily of protein-protein interaction domains.
CASc (cl00042)
  Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
DD (cl14633)
  Death Domain Superfamily of protein-protein interaction domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Casp2 includes H.sapiens CASP2 and R.norvegicus Casp2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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