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HomoloGene:7433. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GADD45B,  H.sapiens
growth arrest and DNA-damage-inducible, beta
NP_056490.2
160 aa
GADD45B,  P.troglodytes
growth arrest and DNA-damage-inducible, beta
XP_001151983.1
160 aa
GADD45B,  M.mulatta
growth arrest and DNA-damage-inducible, beta
XP_001098598.1
160 aa
GADD45B,  C.lupus
growth arrest and DNA-damage-inducible, beta
XP_542187.1
160 aa
GADD45B,  B.taurus
growth arrest and DNA-damage-inducible, beta
NP_001035694.1
160 aa
Gadd45b,  M.musculus
growth arrest and DNA-damage-inducible 45 beta
NP_032681.1
160 aa
Gadd45b,  R.norvegicus
growth arrest and DNA-damage-inducible, beta
NP_001008322.1
160 aa
LOC100859853,  G.gallus
growth arrest and DNA damage-inducible protein GADD45 beta-like
XP_003643868.2
132 aa
gadd45b,  X.tropicalis
growth arrest and DNA-damage-inducible, beta
XP_002941163.2
197 aa
gadd45ba,  D.rerio
growth arrest and DNA-damage-inducible, beta a
NP_998196.1
159 aa
gadd45bb,  D.rerio
growth arrest and DNA-damage-inducible, beta b
NP_001012386.1
158 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

TGFβ signaling induces expression of Gadd45b in retinal ganglion cells.
Liu B, et al. Invest Ophthalmol Vis Sci 54, 1061-9 (2013).
Abnormal expression of GADD45B in human colorectal carcinoma.
Wang L, et al. J Transl Med 10, 215 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ribosomal_L7Ae (pfam01248)
  Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.
Ribosomal_L7Ae (cl00600)
  Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gadd45b includes H.sapiens GADD45B and R.norvegicus Gadd45b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 9 species)
Mammalia - mammals (11 transcripts, 11 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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