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HomoloGene:2724. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TCAP,  H.sapiens
titin-cap
NP_003664.1
167 aa
TCAP,  P.troglodytes
titin-cap
XP_511458.3
143 aa
TCAP,  M.mulatta
titin-cap
XP_001089621.1
167 aa
TCAP,  C.lupus
titin-cap
NP_001128597.1
167 aa
TCAP,  B.taurus
titin-cap (telethonin)
NP_001014915.1
166 aa
Tcap,  M.musculus
titin-cap
NP_035670.2
167 aa
tcap,  X.tropicalis
titin-cap
XP_002940414.1
186 aa
tcap,  D.rerio
titin-cap (telethonin)
XP_684103.1
179 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Muscular dystrophy, limb-girdle, type 2G.
Cardiomyopathy, dilated, 1N.



Publications
Articles associated with genes and sequences of this homology group.

The novel sarcomeric protein telethonin exhibits developmental and functional regulation.
Mason P, et al. Biochem Biophys Res Commun 257, 699-703 (1999).
Transcriptional analysis of the titin cap gene.
Zhang S, et al. Mol Genet Genomics 285, 261-72 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Telethonin (pfam09470)
  Telethonin protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tcap includes H.sapiens TCAP.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (8 transcripts, 8 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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