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HomoloGene:1224. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

AHR,  H.sapiens
aryl hydrocarbon receptor
NP_001612.1
848 aa
AHR,  P.troglodytes
aryl hydrocarbon receptor
XP_003318385.1
850 aa
AHR,  M.mulatta
aryl hydrocarbon receptor
XP_001103903.2
877 aa
AHR,  C.lupus
aryl hydrocarbon receptor
XP_532485.2
853 aa
AHR,  B.taurus
aryl hydrocarbon receptor
NP_001192955.1
844 aa
Ahr,  M.musculus
aryl-hydrocarbon receptor
NP_038492.1
805 aa
Ahr,  R.norvegicus
aryl hydrocarbon receptor
NP_037281.2
853 aa
AHR,  G.gallus
aryl hydrocarbon receptor
NP_989449.1
858 aa
ahr,  X.tropicalis
aryl hydrocarbon receptor
XP_002933348.2
843 aa
ahr1b,  D.rerio
aryl hydrocarbon receptor 1b
NP_001019987.1
940 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.
Contador-Troca M, et al. Carcinogenesis 34, 2683-93 (2013).
Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor.
Shin JH, et al. Proc Natl Acad Sci U S A 110, 12391-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PAS (pfam00989)
  PAS fold.
PAS_3 (pfam08447)
  PAS fold.
PAS (cd00130)
  PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
PAS (pfam00989)
  PAS fold.
PAS_3 (pfam08447)
  PAS fold.
PAS_11 (pfam14598)
  PAS domain.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ahr includes H.sapiens AHR and R.norvegicus Ahr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (12 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

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