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HomoloGene:117. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FSHR,  H.sapiens
follicle stimulating hormone receptor
NP_000136.2
695 aa
FSHR,  P.troglodytes
follicle stimulating hormone receptor
XP_525753.2
695 aa
FSHR,  M.mulatta
follicle stimulating hormone receptor
XP_001114171.1
695 aa
FSHR,  C.lupus
follicle stimulating hormone receptor
XP_538488.2
692 aa
FSHR,  B.taurus
follicle stimulating hormone receptor
NP_776486.1
695 aa
Fshr,  M.musculus
follicle stimulating hormone receptor
NP_038551.3
692 aa
Fshr,  R.norvegicus
follicle stimulating hormone receptor
NP_954707.1
692 aa
FSHR,  G.gallus
follicle stimulating hormone receptor
NP_990410.1
693 aa
fshr,  X.tropicalis
follicle stimulating hormone receptor
XP_002935422.1
692 aa
fshr,  D.rerio
follicle stimulating hormone receptor
NP_001001812.1
668 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ovarian sex cord tumors.
Ovarian dysgenesis 1.
Ovarian response to FSH stimulation.
Ovarian hyperstimulation syndrome.



Publications
Articles associated with genes and sequences of this homology group.

FSH receptor gene variants are rarely associated with premature ovarian failure.
Woad KJ, et al. Reprod Biomed Online 26, 396-9 (2013).
Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors.
Pawlikowski M, et al. Folia Histochem Cytobiol 50, 325-30 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GnHR_trans (pfam12369)
  Gonadotropin hormone receptor transmembrane region.
LRR_8 (pfam13855)
  Leucine rich repeat.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
LRR_5 (pfam13306)
  Leucine rich repeats (6 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fshr includes H.sapiens FSHR and R.norvegicus Fshr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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