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HomoloGene:45654. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

BAZ1A,  H.sapiens
bromodomain adjacent to zinc finger domain, 1A
1556 aa
BAZ1A,  P.troglodytes
bromodomain adjacent to zinc finger domain, 1A
1556 aa
BAZ1A,  C.lupus
bromodomain adjacent to zinc finger domain, 1A
1708 aa
BAZ1A,  B.taurus
bromodomain adjacent to zinc finger domain, 1A
1557 aa
Baz1a,  M.musculus
bromodomain adjacent to zinc finger domain 1A
1552 aa
Baz1a,  R.norvegicus
bromodomain adjacent to zinc finger domain, 1A
1553 aa
BAZ1A,  G.gallus
bromodomain adjacent to zinc finger domain, 1A
1656 aa
baz1a,  X.tropicalis
bromodomain adjacent to zinc finger domain, 1A
1587 aa
baz1a,  D.rerio
bromodomain adjacent to zinc finger domain, 1A
717 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Role for hACF1 in the G2/M damage checkpoint.
Sánchez-Molina S, et al. Nucleic Acids Res 39, 8445-56 (2011).
Chromatin remodelers act globally, sequence positions nucleosomes locally.
Partensky PD & Narlikar GJ. J Mol Biol 391, 12-25 (2009).
A 'loop recapture' mechanism for ACF-dependent nucleosome remodeling.
Strohner R, et al. Nat Struct Mol Biol 12, 683-90 (2005).
A family of chromatin remodeling factors related to Williams syndrome transcription factor.
Bochar DA, et al. Proc Natl Acad Sci U S A 97, 1038-43 (2000).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHD (pfam00628)
WAC_Acf1_DNA_bd (pfam10537)
  ATP-utilizing chromatin assembly and remodelling N-terminal.
DDT (cl02674)
  DDT domain.
Nop25 (pfam09805)
  Nucleolar protein 12 (25kDa).
WHIM1 (pfam15612)
  WSTF, HB1, Itc1p, MBD9 motif 1.
WHIM3 (pfam15614)
  WSTF, HB1, Itc1p, MBD9 motif 3.
Bromodomain (cl02556)
  Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
PHD (cl17445)

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Baz1a includes H.sapiens BAZ1A and R.norvegicus Baz1a.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (20 transcripts, 13 species)
Actinopterygii - bony fishes (10 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Insecta - insects (6 transcripts, 6 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Gastropoda - gastropods (2 transcripts, 1 species)

Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinoidea - sea urchins (2 transcripts, 2 species)

Chromadorea - nematodes (1 transcript, 1 species)




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