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HomoloGene:129864. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

RLN2,  H.sapiens
relaxin 2
185 aa
RLN2,  P.troglodytes
relaxin 2
185 aa
RLN2,  M.mulatta
relaxin 2
185 aa
RLN1,  C.lupus
relaxin 1
177 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.
Hampel U, et al. Invest Ophthalmol Vis Sci 53, 7780-90 (2012).
Human relaxin-2: historical perspectives and role in cancer biology.
Nair VB, et al. Amino Acids 43, 1131-40 (2012).
Relaxin-2 may offer therapeutic advantages in end-stage heart failure.
Zhao Z, et al. Int J Cardiol 157, 432-3 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IlGF_like (cl02453)
  Insulin/insulin-like growth factor/relaxin family; insulin family of proteins. Members include a number of active peptides which are evolutionary related including insulin, relaxin, prorelaxin, insulin-like growth factors I and II, mammalian Leydig ...

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (3 transcripts, 3 species)




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