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HomoloGene:1387. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CCR7,  H.sapiens
chemokine (C-C motif) receptor 7
NP_001829.1
378 aa
CCR7,  P.troglodytes
chemokine (C-C motif) receptor 7
XP_511477.3
378 aa
CCR7,  M.mulatta
chemokine (C-C motif) receptor 7
NP_001028056.1
378 aa
CCR7,  C.lupus
chemokine (C-C motif) receptor 7
XP_548131.2
379 aa
CCR7,  B.taurus
chemokine (C-C motif) receptor 7
NP_001020101.2
379 aa
Ccr7,  M.musculus
chemokine (C-C motif) receptor 7
NP_031745.2
378 aa
Ccr7,  R.norvegicus
chemokine (C-C motif) receptor 7
NP_955783.1
378 aa
CCR7,  G.gallus
chemokine (C-C motif) receptor 7
NP_001185681.1
374 aa
ccr7,  X.tropicalis
chemokine (C-C motif) receptor 7
XP_004918750.1
374 aa
ccr7,  D.rerio
chemokine (C-C motif) receptor 7
NP_001092213.1
372 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Human eosinophils express functional CCR7.
Akuthota P, et al. Am J Respir Cell Mol Biol 48, 758-64 (2013).
CCR7+ central and CCR7- effector memory CD4+ T cells in human cutaneous leishmaniasis.
Keshavarz Valian H, et al. J Clin Immunol 33, 220-34 (2013).
CCR7-independent transport of skin antigens occurs in the dermis.
Yoshino M, et al. Eur J Immunol 42, 1459-67 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ccr7 includes H.sapiens CCR7 and R.norvegicus Ccr7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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