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HomoloGene:28. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

AR,  H.sapiens
androgen receptor
920 aa
AR,  M.mulatta
androgen receptor
895 aa
AR,  C.lupus
androgen receptor
907 aa
AR,  B.taurus
androgen receptor
890 aa
Ar,  M.musculus
androgen receptor
899 aa
Ar,  R.norvegicus
androgen receptor
902 aa
AR,  G.gallus
androgen receptor
703 aa
ar,  X.tropicalis
androgen receptor
788 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Prostate cancer, susceptibility to.
Androgen insensitivity.
Hypospadias, perineal.
Spinal and bulbar muscular atrophy of Kennedy.
Breast cancer, male, with Reifenstein syndrome.
Prostate cancer.

Articles associated with genes and sequences of this homology group.

Visualising androgen receptor activity in male and female mice.
Dart DA, et al. PLoS One 8, e71694 (2013).
Androgen receptors in early and castration resistant prostate cancer: friend or foe?
Pelekanou V, et al. Hormones (Athens) 12, 224-35 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Androgen_recep (pfam02166)
  Androgen receptor.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ar includes H.sapiens AR and R.norvegicus Ar.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (18 transcripts, 15 species)
Actinopterygii - bony fishes (14 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)




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