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HomoloGene:14238. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RAD51C,  H.sapiens
RAD51 paralog C
NP_478123.1
376 aa
RAD51C,  P.troglodytes
RAD51 homolog C (S. cerevisiae)
XP_511913.3
337 aa
RAD51C,  M.mulatta
RAD51 homolog C (S. cerevisiae)
XP_001104781.2
337 aa
RAD51C,  C.lupus
RAD51 paralog C
XP_537695.4
392 aa
RAD51C,  B.taurus
RAD51 paralog C
XP_002695646.3
441 aa
Rad51c,  M.musculus
RAD51 homolog C
NP_444499.1
366 aa
Rad51c,  R.norvegicus
RAD51 paralog C
NP_001123249.1
366 aa
RAD51C,  G.gallus
RAD51 homolog C (S. cerevisiae)
XP_415870.3
366 aa
rad51c,  X.tropicalis
RAD51 homolog C (S. cerevisiae)
XP_004911732.1
369 aa
rad51c,  X.tropicalis
RAD51 paralog C
NP_001016923.1
361 aa
rad51c,  D.rerio
rad51 homolog C (S. cerevisiae)
NP_001006101.1
362 aa
RAD51C,  A.thaliana
RAD51C
NP_566040.1
363 aa
Os01g0578000,  O.sativa
Os01g0578000
NP_001043394.1
349 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fanconi anemia, complementation group 0.
Breast-ovarian cancer, familial, susceptibility to, 3.



Publications
Articles associated with genes and sequences of this homology group.

Germline mutations in RAD51C in Jewish high cancer risk families.
Kushnir A, et al. Breast Cancer Res Treat 136, 869-74 (2012).
Germline RAD51C mutations in ovarian cancer susceptibility.
Coulet F, et al. Clin Genet 83, 332-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RecA-like_NTPases (cl17233)
  RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rad51c includes H.sapiens RAD51C and R.norvegicus Rad51c.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (13 transcripts, 13 species)
Liliopsida - monocots (8 transcripts, 6 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Bryopsida - mosses (1 transcript, 1 species)

 

 

 

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