Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:74563. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ABCC4,  H.sapiens
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NP_005836.2
1325 aa
ABCC4,  P.troglodytes
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
XP_001137006.1
1325 aa
ABCC4,  C.lupus
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NP_001184103.1
1326 aa
Abcc4,  M.musculus
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NP_001028508.2
1325 aa
Abcc4,  R.norvegicus
ATP-binding cassette, subfamily C (CFTR/MRP), member 4
NP_596902.1
1325 aa
ABCC4,  G.gallus
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NP_001025990.1
1330 aa
abcc4,  X.tropicalis
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
XP_002939329.2
1324 aa
abcc4,  D.rerio
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NP_001007039.1
1327 aa
CG7627,  D.melanogaster
CG7627
NP_609215.3
1355 aa
CG31792,  D.melanogaster
CG31792
NP_001260548.1
1323 aa
CG4562,  D.melanogaster
CG4562
NP_001262747.1
1408 aa
Mrp4,  D.melanogaster
Multidrug resistance protein 4 ortholog
NP_650086.2
1316 aa
CG31793,  D.melanogaster
CG31793
NP_609930.4
1307 aa
CG9270,  D.melanogaster
CG9270
NP_995741.2
1292 aa
l(2)03659,  D.melanogaster
lethal (2) 03659
NP_001260823.1
1374 aa
AgaP_AGAP006427,  A.gambiae
AgaP_AGAP006427
XP_316463.3
1389 aa
mrp-6,  C.elegans
mrp-6
NP_508710.3
1415 aa
MRP3,  A.thaliana
MRP3
NP_187915.1
1514 aa
MRP8,  A.thaliana
MRP8
NP_187916.3
1466 aa
MRP7,  A.thaliana
MRP7
NP_187917.3
1493 aa
Os01g0173900,  O.sativa
Os01g0173900
NP_001042159.1
1505 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ABCC4 is regulated by microRNA-124a and microRNA-506.
Markova SM & Kroetz DL. Biochem Pharmacol 87, 515-22 (2014).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_membrane_2 (cl00549)
  ABC transporter transmembrane region 2.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abcc4 includes H.sapiens ABCC4 and R.norvegicus Abcc4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (51 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 1 species)

Chordata
Mammalia - mammals (26 transcripts, 8 species)
Actinopterygii - bony fishes (18 transcripts, 9 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (11 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (8 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (13 transcripts, 10 species)
Liliopsida - monocots (9 transcripts, 6 species)
Coniferopsida - conifers (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

Support Center