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HomoloGene:20553. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MYH3,  H.sapiens
myosin, heavy chain 3, skeletal muscle, embryonic
NP_002461.2
1940 aa
MYH3,  P.troglodytes
myosin, heavy chain 3, skeletal muscle, embryonic
XP_003315696.1
1854 aa
MYH3,  M.mulatta
myosin, heavy chain 3, skeletal muscle, embryonic
XP_001114005.2
1945 aa
MYH3,  C.lupus
myosin, heavy chain 3, skeletal muscle, embryonic
NP_001107184.1
1920 aa
MYH3,  B.taurus
myosin, heavy chain 3, skeletal muscle, embryonic
NP_001095305.1
1940 aa
Myh3,  M.musculus
myosin, heavy polypeptide 3, skeletal muscle, embryonic
NP_001093105.1
1940 aa
Myh3,  R.norvegicus
myosin, heavy chain 3, skeletal muscle, embryonic
NP_036736.1
1940 aa
LOC100495065,  X.tropicalis
myosin-3-like
XP_002937051.2
1942 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Arthrogryposis, distal, type 2A.
Arthrogryposis, distal, type 2B.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Myosin_N (pfam02736)
  Myosin N-terminal SH3-like domain.
MMtag (pfam10159)
  Kinase phosphorylation protein.
Filament (pfam00038)
  Intermediate filament protein.
Myosin_N (pfam02736)
  Myosin N-terminal SH3-like domain.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
MIT_CorA-like (cl00459)
  metal ion transporter CorA-like divalent cation transporter superfamily.
GrpE (cl03075)
  GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.
COG6 (cl19764)
  Conserved oligomeric complex COG6.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myh3 includes H.sapiens MYH3 and R.norvegicus Myh3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 7 species)
Mammalia - mammals (10 transcripts, 9 species)
Amphibia - amphibians (7 transcripts, 2 species)
Cephalochordata - lancelets (4 transcripts, 1 species)
Amniota - vertebrates (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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