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HomoloGene:20553. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

MYH3,  H.sapiens
myosin, heavy chain 3, skeletal muscle, embryonic
1940 aa
MYH3,  P.troglodytes
myosin, heavy chain 3, skeletal muscle, embryonic
1854 aa
MYH3,  M.mulatta
myosin, heavy chain 3, skeletal muscle, embryonic
1945 aa
MYH3,  C.lupus
myosin, heavy chain 3, skeletal muscle, embryonic
1920 aa
MYH3,  B.taurus
myosin, heavy chain 3, skeletal muscle, embryonic
1940 aa
Myh3,  M.musculus
myosin, heavy polypeptide 3, skeletal muscle, embryonic
1940 aa
Myh3,  R.norvegicus
myosin, heavy chain 3, skeletal muscle, embryonic
1940 aa
LOC100495065,  X.tropicalis
1942 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Arthrogryposis, distal, type 2A.
Arthrogryposis, distal, type 2B.

Articles associated with genes and sequences of this homology group.

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Myosin_N (pfam02736)
  Myosin N-terminal SH3-like domain.
MMtag (pfam10159)
  Kinase phosphorylation protein.
Filament (pfam00038)
  Intermediate filament protein.
Myosin_N (pfam02736)
  Myosin N-terminal SH3-like domain.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
MIT_CorA-like (cl00459)
  metal ion transporter CorA-like divalent cation transporter superfamily.
GrpE (cl03075)
  GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.
COG6 (cl19764)
  Conserved oligomeric complex COG6.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myh3 includes H.sapiens MYH3 and R.norvegicus Myh3.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (13 transcripts, 7 species)
Mammalia - mammals (10 transcripts, 9 species)
Amphibia - amphibians (7 transcripts, 2 species)
Cephalochordata - lancelets (4 transcripts, 1 species)
Amniota - vertebrates (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Gastropoda - gastropods (1 transcript, 1 species)

Hirudinida - segmented worms (1 transcript, 1 species)

Eudicotyledons - eudicots (1 transcript, 1 species)




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