Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:2390. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SYK,  H.sapiens
spleen tyrosine kinase
NP_001167638.1
635 aa
SYK,  P.troglodytes
spleen tyrosine kinase
XP_520123.4
592 aa
SYK,  M.mulatta
spleen tyrosine kinase
XP_001100834.1
635 aa
SYK,  C.lupus
spleen tyrosine kinase
XP_005616010.1
633 aa
SYK,  B.taurus
spleen tyrosine kinase
NP_001032542.1
605 aa
Syk,  M.musculus
spleen tyrosine kinase
NP_001185906.1
629 aa
Syk,  R.norvegicus
spleen tyrosine kinase
NP_036890.1
629 aa
SYK,  G.gallus
spleen tyrosine kinase
NP_001026601.1
613 aa
syk,  X.tropicalis
spleen tyrosine kinase
XP_002937073.2
631 aa
syk,  D.rerio
spleen tyrosine kinase
NP_998008.1
586 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Syk is low-expressed in non-small-cell lung cancer and inversely correlates with patient's survival.
Peng C, et al. Acta Biochim Biophys Sin (Shanghai) 45, 149-51 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
SH2 (cl15255)
  Src homology 2 (SH2) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Syk includes H.sapiens SYK and R.norvegicus Syk.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (10 transcripts, 8 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

Support Center