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HomoloGene:9192. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SETBP1,  H.sapiens
SET binding protein 1
NP_056374.2
1596 aa
SETBP1,  P.troglodytes
SET binding protein 1
XP_512106.2
1596 aa
SETBP1,  M.mulatta
SET-binding protein-like
XP_002808207.1
1596 aa
SETBP1,  C.lupus
SET binding protein 1
XP_547594.2
1539 aa
SETBP1,  B.taurus
SET binding protein 1
XP_003587826.1
1595 aa
Setbp1,  M.musculus
SET binding protein 1
NP_444329.2
1582 aa
Setbp1,  R.norvegicus
SET binding protein 1
XP_006255044.1
1358 aa
SETBP1,  G.gallus
SET binding protein 1
XP_001233854.3
1612 aa
setbp1,  D.rerio
SET binding protein 1
XP_005165732.1
1438 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukemia, acute T-cell lymphoblastic.



Publications
Articles associated with genes and sequences of this homology group.

Somatic SETBP1 mutations in myeloid malignancies.
Makishima H, et al. Nat Genet 45, 942-6 (2013).
SETBP1 mutation analysis in 944 patients with MDS and AML.
Thol F, et al. Leukemia 27, 2072-5 (2013).
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia.
Piazza R, et al. Nat Genet 45, 18-24 (2013).
SETBP1 mutations in two Thai patients with Schinzel-Giedion syndrome.
Suphapeetiporn K, et al. Clin Genet 79, 391-3 (2011).




Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Setbp1 includes H.sapiens SETBP1 and R.norvegicus Setbp1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 7 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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