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HomoloGene:475. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

FCGR1A,  H.sapiens
Fc fragment of IgG, high affinity Ia, receptor (CD64)
374 aa
FCGR1A,  P.troglodytes
Fc fragment of IgG, high affinity Ia, receptor (CD64)
373 aa
FCGR1A,  C.lupus
Fc fragment of IgG, high affinity Ia, receptor (CD64)
372 aa
FCGR1A,  B.taurus
Fc fragment of IgG, high affinity Ia, receptor (CD64)
349 aa
Fcgr1,  M.musculus
Fc receptor, IgG, high affinity I
404 aa
Fcgr1a,  R.norvegicus
Fc fragment of IgG, high affinity Ia, receptor (CD64)
353 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

IgG receptor I, phagocytic, familial deficiency of.

Articles associated with genes and sequences of this homology group.

Engineering of recombinant human Fcγ receptor I by directed evolution.
Asaoka Y, et al. Protein Eng Des Sel 25, 835-42 (2012).
Neutrophil CD64 as a sepsis biomarker.
Hoffmann JJ. Biochem Med (Zagreb) 21, 282-90 (2011).
Expression of CD64 (FcγRI) in skin of patients with acute GVHD.
van Royen-Kerkhof A, et al. Bone Marrow Transplant 46, 1566-9 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IG_like (smart00410)
  Immunoglobulin like.
ig (pfam00047)
  Immunoglobulin domain.
Ig_3 (pfam13927)
  Immunoglobulin domain.
Ig (cl11960)
  Immunoglobulin domain.
Ig (cl11960)
  Immunoglobulin domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fcgr1 includes H.sapiens FCGR1A and R.norvegicus Fcgr1a.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (7 transcripts, 7 species)




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