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HomoloGene:68220. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GFPT1,  H.sapiens
glutamine--fructose-6-phosphate transaminase 1
NP_001231639.1
699 aa
GFPT1,  P.troglodytes
glutamine--fructose-6-phosphate transaminase 1
XP_003949855.1
699 aa
GFPT1,  M.mulatta
glutamine--fructose-6-phosphate transaminase 1
XP_001096250.2
681 aa
GFPT1,  C.lupus
glutamine--fructose-6-phosphate transaminase 1
XP_005626234.1
712 aa
GFPT1,  B.taurus
glutamine--fructose-6-phosphate transaminase 1
NP_001103431.1
681 aa
Gfpt1,  M.musculus
glutamine fructose-6-phosphate transaminase 1
NP_038556.1
681 aa
Gfpt1,  R.norvegicus
glutamine fructose-6-phosphate transaminase 1
NP_001005879.1
681 aa
GFPT1,  G.gallus
glutamine--fructose-6-phosphate transaminase 1
NP_001026053.1
699 aa
gfpt1,  X.tropicalis
glutamine--fructose-6-phosphate transaminase 1
XP_002935349.1
697 aa
gfpt1,  D.rerio
glutamine-fructose-6-phosphate transaminase 1
NP_001030153.1
682 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
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Publications
Articles associated with genes and sequences of this homology group.

Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells.
Cooksey RC, et al. Am J Physiol Endocrinol Metab 290, E334-40 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Gn_AT_II (cl00319)
  Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to ...
SIS (cl00389)
  SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gfpt1 includes H.sapiens GFPT1 and R.norvegicus Gfpt1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (10 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (2 transcripts, 2 species)
Eudicotyledons - eudicots (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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