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HomoloGene:8975. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

ZNF365,  H.sapiens
zinc finger protein 365
407 aa
ZNF365,  M.mulatta
zinc finger protein 365
407 aa
ZNF365,  C.lupus
zinc finger protein 365
408 aa
LOC521207,  B.taurus
protein ZNF365-like
405 aa
Zfp365,  M.musculus
zinc finger protein 365
408 aa
Zfp365,  R.norvegicus
zinc finger protein 365
408 aa
ZNF365,  G.gallus
zinc finger protein 365
390 aa
znf365,  X.tropicalis
zinc finger protein 365
397 aa
LOC799320,  D.rerio
protein ZNF365-like
345 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Nephrolithiasis, uric acid, susceptibility to.
uric acid nephrolithiasis.

Articles associated with genes and sequences of this homology group.

ZNF365 promotes stability of fragile sites and telomeres.
Zhang Y, et al. Cancer Discov 3, 798-811 (2013).
Variants in ZNF365 isoform D are associated with Crohn's disease.
Haritunians T, et al. Gut 60, 1060-7 (2011).
Identification of a new candidate locus for uric acid nephrolithiasis.
Ombra MN, et al. Am J Hum Genet 68, 1119-29 (2001).
Characterization of Su48, a centrosome protein essential for cell division.
Wang Q, et al. Proc Natl Acad Sci U S A 103, 6512-7 (2006).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAA_32 (pfam13654)
  AAA domain.
xseA (PRK00286)
  exodeoxyribonuclease VII large subunit; Reviewed.
AAA_32 (pfam13654)
  AAA domain.
DHR2_DOCK (cl06123)
  Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
DUF2317 (cl19511)
  Uncharacterized protein conserved in bacteria (DUF2317).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Zfp365 includes H.sapiens ZNF365 and R.norvegicus Zfp365.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)




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