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HomoloGene:8975. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ZNF365,  H.sapiens
zinc finger protein 365
NP_055766.2
407 aa
ZNF365,  M.mulatta
zinc finger protein 365
XP_001093064.1
407 aa
ZNF365,  C.lupus
zinc finger protein 365
XP_003639034.1
408 aa
LOC521207,  B.taurus
protein ZNF365-like
XP_005226375.1
405 aa
Zfp365,  M.musculus
zinc finger protein 365
NP_848794.1
408 aa
Zfp365,  R.norvegicus
zinc finger protein 365
NP_001020316.1
408 aa
ZNF365,  G.gallus
zinc finger protein 365
NP_001186476.1
390 aa
znf365,  X.tropicalis
zinc finger protein 365
XP_002939589.1
397 aa
LOC799320,  D.rerio
protein ZNF365-like
XP_001339691.1
345 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Nephrolithiasis, uric acid, susceptibility to.
uric acid nephrolithiasis.



Publications
Articles associated with genes and sequences of this homology group.

ZNF365 promotes stability of fragile sites and telomeres.
Zhang Y, et al. Cancer Discov 3, 798-811 (2013).
Variants in ZNF365 isoform D are associated with Crohn's disease.
Haritunians T, et al. Gut 60, 1060-7 (2011).
Identification of a new candidate locus for uric acid nephrolithiasis.
Ombra MN, et al. Am J Hum Genet 68, 1119-29 (2001).
Characterization of Su48, a centrosome protein essential for cell division.
Wang Q, et al. Proc Natl Acad Sci U S A 103, 6512-7 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAA_32 (pfam13654)
  AAA domain.
xseA (PRK00286)
  exodeoxyribonuclease VII large subunit; Reviewed.
AAA_32 (pfam13654)
  AAA domain.
DHR2_DOCK (cl06123)
  Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
DUF2317 (cl19511)
  Uncharacterized protein conserved in bacteria (DUF2317).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Zfp365 includes H.sapiens ZNF365 and R.norvegicus Zfp365.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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