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HomoloGene:3825. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DLX5,  H.sapiens
distal-less homeobox 5
NP_005212.1
289 aa
DLX5,  P.troglodytes
distal-less homeobox 5
XP_519218.2
289 aa
DLX5,  M.mulatta
distal-less homeobox 5
XP_001090332.1
289 aa
DLX5,  C.lupus
distal-less homeobox 5
XP_850412.1
289 aa
DLX5,  B.taurus
distal-less homeobox 5
NP_001068781.1
289 aa
Dlx5,  M.musculus
distal-less homeobox 5
NP_034186.2
289 aa
Dlx5,  R.norvegicus
distal-less homeobox 5
NP_037075.1
289 aa
DLX5,  G.gallus
distal-less homeobox 5
NP_989490.1
286 aa
dlx5,  X.tropicalis
distal-less homeobox 5
NP_001004778.1
289 aa
dlx5a,  D.rerio
distal-less homeobox gene 5a
NP_571381.1
283 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Ochratoxin A induces craniofacial malformation in mice acting on Dlx5 gene expression.
Napoletano M, et al. Front Biosci (Elite Ed) 2, 133-42 (2010).
Increased bone resorption and osteopenia in Dlx5 heterozygous mice.
Samee N, et al. J Cell Biochem 107, 865-72 (2009).
Phenotypic analysis of Dlx5 overexpression in post-natal bone.
Zhang J, et al. J Dent Res 87, 45-50 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DLL_N (pfam12413)
  Homeobox protein distal-less-like N terminal.
DLL_N (pfam12413)
  Homeobox protein distal-less-like N terminal.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dlx5 includes H.sapiens DLX5 and R.norvegicus Dlx5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (3 transcripts, 2 species)
Hyperoartia - vertebrates (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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