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HomoloGene:56424. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PRKCB,  H.sapiens
protein kinase C, beta
NP_002729.2
673 aa
PRKCB,  P.troglodytes
protein kinase C, beta
XP_003315067.1
670 aa
PRKCB,  M.mulatta
protein kinase C, beta
XP_001096447.1
673 aa
PRKCB,  C.lupus
protein kinase C, beta
XP_005622125.1
741 aa
PRKCB,  B.taurus
protein kinase C, beta
NP_777012.1
673 aa
Prkcb,  M.musculus
protein kinase C, beta
NP_032881.1
673 aa
Prkcb,  R.norvegicus
protein kinase C, beta
NP_036845.3
673 aa
PRKCB,  G.gallus
protein kinase C, beta
XP_414868.4
614 aa
prkcb,  X.tropicalis
protein kinase C, beta
NP_001103513.1
670 aa
prkcbb,  D.rerio
protein kinase C, beta b
NP_957272.1
670 aa
pck1,  S.pombe
pck1
NP_593737.2
988 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PKCβII modulation of myocyte contractile performance.
Hwang H, et al. J Mol Cell Cardiol 53, 176-86 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
C2 (cl14603)
  C2 domain.
C1 (cl00040)
  Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
HR1 (cl00087)
  Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
C2 (cl14603)
  C2 domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkcb includes H.sapiens PRKCB and R.norvegicus Prkcb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 14 species)
Actinopterygii - bony fishes (13 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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