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HomoloGene:1838. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MTAP,  H.sapiens
methylthioadenosine phosphorylase
NP_002442.2
283 aa
MTAP,  P.troglodytes
methylthioadenosine phosphorylase
XP_001153022.1
283 aa
MTAP,  M.mulatta
methylthioadenosine phosphorylase
XP_001107077.1
283 aa
MTAP,  C.lupus
methylthioadenosine phosphorylase
XP_531959.3
284 aa
MTAP,  B.taurus
methylthioadenosine phosphorylase
XP_002689552.1
283 aa
Mtap,  M.musculus
methylthioadenosine phosphorylase
NP_077753.1
283 aa
MTAP,  G.gallus
methylthioadenosine phosphorylase
NP_001026775.2
280 aa
mtap,  X.tropicalis
methylthioadenosine phosphorylase
NP_001011495.1
280 aa
mtap,  D.rerio
methylthioadenosine phosphorylase
NP_956848.1
280 aa
CG4802,  D.melanogaster
CG4802
NP_001261049.1
360 aa
AgaP_AGAP005129,  A.gambiae
AgaP_AGAP005129
XP_314011.4
278 aa
B0228.7,  C.elegans
B0228.7
NP_495629.2
288 aa
MEU1,  S.cerevisiae
MEU1
NP_013117.1
337 aa
KLLA0F15664g,  K.lactis
KLLA0F15664g
XP_455784.1
338 aa
SPAC16C9.02c,  S.pombe
SPAC16C9.02c
NP_593076.1
307 aa
MGG_06498,  M.oryzae
MGG_06498
XP_003717062.1
319 aa
NCU03963,  N.crassa
NCU03963
XP_957602.1
310 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Lack of expression of MTAP in uncommon T-cell lymphomas.
Bertino JR, et al. Clin Lymphoma Myeloma Leuk 12, 306-9 (2012).
[Detection of MTAP protein and gene expression in non-small cell lung cancer].
Li S, et al. Zhongguo Fei Ai Za Zhi 14, 151-5 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pnp (COG0005)
  Purine nucleoside phosphorylase [Nucleotide transport and metabolism].
PNP_UDP_1 (cl00303)
  Phosphorylase superfamily.
PNP_UDP_1 (cl00303)
  Phosphorylase superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mtap includes H.sapiens MTAP.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 14 species)
Actinopterygii - bony fishes (9 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 11 species)
Arachnida - arachnids (4 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (4 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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