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HomoloGene:110440. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ACY1,  H.sapiens
aminoacylase 1
NP_000657.1
408 aa
ACY1,  P.troglodytes
aminoacylase 1
XP_003950170.1
498 aa
ACY1,  C.lupus
aminoacylase 1
XP_533806.2
408 aa
ACY1,  B.taurus
aminoacylase 1
NP_001070583.1
373 aa
Acy1,  M.musculus
aminoacylase 1
NP_079647.1
408 aa
Acy1,  R.norvegicus
aminoacylase 1
NP_001005383.1
408 aa
ACY1,  G.gallus
aminoacylase 1
XP_004944531.1
441 aa
acy1.1,  X.tropicalis
aminoacylase 1, gene 1
NP_001011406.1
407 aa
LOC100001620,  D.rerio
aminoacylase-1A-like
XP_001922589.1
420 aa
acy1,  D.rerio
aminoacylase 1
NP_001259009.1
420 aa
CG6465,  D.melanogaster
CG6465
NP_650004.1
401 aa
CG6726,  D.melanogaster
CG6726
NP_732822.1
401 aa
CG6738,  D.melanogaster
CG6738
NP_651124.1
401 aa
CG6733,  D.melanogaster
CG6733
NP_651123.1
401 aa
CG17109,  D.melanogaster
CG17109
NP_651122.2
400 aa
CG17110,  D.melanogaster
CG17110
NP_651121.1
402 aa
AgaP_AGAP000679,  A.gambiae
AgaP_AGAP000679
XP_311208.4
409 aa
C06A6.4,  C.elegans
C06A6.4
NP_001021301.1
411 aa
C10C5.3,  C.elegans
C10C5.3
NP_501650.1
399 aa
C10C5.5,  C.elegans
C10C5.5
NP_501652.2
397 aa
C10C5.4,  C.elegans
C10C5.4
NP_501651.1
397 aa
AT4G38220,  A.thaliana
AT4G38220
NP_849516.1
433 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Aminoacylase 1 deficiency.



Publications
Articles associated with genes and sequences of this homology group.

The molecular basis of aminoacylase 1 deficiency.
Sommer A, et al. Biochim Biophys Acta 1812, 685-90 (2011).
Differential aminoacylase expression in neuroblastoma.
Long PM, et al. Int J Cancer 129, 1322-30 (2011).
Neurological findings in aminoacylase 1 deficiency.
Sass JO, et al. Neurology 68, 2151-3 (2007).
Acylase 1 expression in rat intestinal crypt--villus axis.
Cigna N, et al. Cell Biol Int 31, 966-73 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ac-peptdase-euk (TIGR01880)
  N-acyl-L-amino-acid amidohydrolase.
Zinc_peptidase_like (cl14876)
  Zinc peptidases M18, M20, M28, and M42.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Acy1 includes H.sapiens ACY1 and R.norvegicus Acy1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 12 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 6 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (6 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (29 transcripts, 28 species)
Liliopsida - monocots (11 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Bryopsida - mosses (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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