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HomoloGene:43672. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PTK7,  H.sapiens
protein tyrosine kinase 7
NP_690621.1
1014 aa
PTK7,  P.troglodytes
PTK7 protein tyrosine kinase 7
XP_003311345.1
1030 aa
PTK7,  M.mulatta
PTK7 protein tyrosine kinase 7
XP_002803792.1
1030 aa
PTK7,  C.lupus
protein tyrosine kinase 7
XP_538929.2
1070 aa
PTK7,  B.taurus
PTK7 protein tyrosine kinase 7
NP_001179894.1
1070 aa
Ptk7,  M.musculus
PTK7 protein tyrosine kinase 7
NP_780377.1
1062 aa
PTK7,  G.gallus
PTK7 protein tyrosine kinase 7
NP_001026206.1
1051 aa
LOC100487595,  X.tropicalis
inactive tyrosine-protein kinase 7-like
XP_002944477.2
444 aa
ptk7b,  D.rerio
protein tyrosine kinase 7b
XP_005173100.1
412 aa
otk,  D.melanogaster
off-track
NP_523705.2
1033 aa
AgaP_AGAP011489,  A.gambiae
AgaP_AGAP011489
XP_317813.4
803 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PTK7 expression in triple-negative breast cancer.
Ataseven B, et al. Anticancer Res 33, 3759-63 (2013).
PTK7 marks the first human developmental EMT in vitro.
Chan DN, et al. PLoS One 7, e50432 (2012).
The many roles of PTK7: a versatile regulator of cell-cell communication.
Peradziryi H, et al. Arch Biochem Biophys 524, 71-6 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
I-set (pfam07679)
  Immunoglobulin I-set domain.
IGc2 (smart00408)
  Immunoglobulin C-2 Type.
IG (smart00409)
  Immunoglobulin.
IG_like (smart00410)
  Immunoglobulin like.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Ig (cl11960)
  Immunoglobulin domain.
I-set (pfam07679)
  Immunoglobulin I-set domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ptk7 includes H.sapiens PTK7 and R.norvegicus Ptk7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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