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HomoloGene:68095. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HPGD,  H.sapiens
hydroxyprostaglandin dehydrogenase 15-(NAD)
NP_000851.2
266 aa
HPGD,  P.troglodytes
hydroxyprostaglandin dehydrogenase 15-(NAD)
XP_517542.2
266 aa
HPGD,  M.mulatta
hydroxyprostaglandin dehydrogenase 15-(NAD)
XP_001087957.1
266 aa
HPGD,  C.lupus
hydroxyprostaglandin dehydrogenase 15-(NAD)
XP_543199.1
266 aa
HPGD,  B.taurus
hydroxyprostaglandin dehydrogenase 15-(NAD)
NP_001029591.1
266 aa
Hpgd,  M.musculus
hydroxyprostaglandin dehydrogenase 15 (NAD)
NP_032304.2
269 aa
Hpgd,  R.norvegicus
hydroxyprostaglandin dehydrogenase 15 (NAD)
NP_077366.2
266 aa
HPGD,  G.gallus
hydroxyprostaglandin dehydrogenase 15-(NAD)
NP_001264713.1
265 aa
hpgd,  X.tropicalis
hydroxyprostaglandin dehydrogenase 15-(NAD)
NP_001007992.1
264 aa
LOC565975,  D.rerio
15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like
XP_694331.5
261 aa
AgaP_AGAP001753,  A.gambiae
AgaP_AGAP001753
XP_321329.4
252 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cranioosteoarthropathy.
Hypertrophic osteoarthropathy, primary, autosomal recessive.



Publications
Articles associated with genes and sequences of this homology group.

15-PGDH is reduced and induces apoptosis and cell cycle arrest in gastric carcinoma.
Lou LH, et al. World J Gastroenterol 18, 1028-37 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hpgd includes H.sapiens HPGD and R.norvegicus Hpgd.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 14 species)
Actinopterygii - bony fishes (13 transcripts, 11 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (25 transcripts, 9 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (5 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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