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HomoloGene:22799. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IMPA2,  H.sapiens
inositol(myo)-1(or 4)-monophosphatase 2
NP_055029.1
288 aa
IMPA2,  P.troglodytes
inositol(myo)-1(or 4)-monophosphatase 2
XP_512020.2
288 aa
IMPA2,  M.mulatta
inositol(myo)-1(or 4)-monophosphatase 2
XP_001096318.1
288 aa
IMPA2,  C.lupus
inositol(myo)-1(or 4)-monophosphatase 2
XP_005623149.1
269 aa
IMPA2,  B.taurus
inositol(myo)-1(or 4)-monophosphatase 2
NP_001179211.1
288 aa
Impa2,  M.musculus
inositol (myo)-1(or 4)-monophosphatase 2
NP_444491.1
290 aa
Impa2,  R.norvegicus
inositol (myo)-1(or 4)-monophosphatase 2
NP_757378.1
290 aa
IMPA2,  G.gallus
inositol(myo)-1(or 4)-monophosphatase 2
XP_419118.1
292 aa
impa2,  X.tropicalis
inositol(myo)-1(or 4)-monophosphatase 2
XP_002936126.1
309 aa
impa2,  D.rerio
inositol(myo)-1(or 4)-monophosphatase 2
NP_001018408.1
275 aa
CG9389,  D.melanogaster
CG9389
NP_649295.1
596 aa
MGG_15250,  M.oryzae
MGG_15250
XP_003713000.1
330 aa
NCU06022,  N.crassa
NCU06022
XP_959612.1
340 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder.
Bloch PJ, et al. Prog Neuropsychopharmacol Biol Psychiatry 34, 1515-9 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FIG (cl00289)
  FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Impa2 includes H.sapiens IMPA2 and R.norvegicus Impa2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)
Arachnida - arachnids (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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