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HomoloGene:3637. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MTOR,  H.sapiens
mechanistic target of rapamycin (serine/threonine kinase)
NP_004949.1
2549 aa
MTOR,  P.troglodytes
mechanistic target of rapamycin (serine/threonine kinase)
XP_003949341.1
2567 aa
MTOR,  C.lupus
mechanistic target of rapamycin (serine/threonine kinase)
XP_005618060.1
2550 aa
MTOR,  B.taurus
mechanistic target of rapamycin (serine/threonine kinase)
XP_005217047.1
2560 aa
Mtor,  M.musculus
mechanistic target of rapamycin (serine/threonine kinase)
NP_064393.2
2549 aa
Mtor,  R.norvegicus
mechanistic target of rapamycin (serine/threonine kinase)
NP_063971.1
2549 aa
MTOR,  G.gallus
mechanistic target of rapamycin (serine/threonine kinase)
XP_417614.3
2521 aa
mtor,  X.tropicalis
mechanistic target of rapamycin (serine/threonine kinase)
XP_004916088.1
2525 aa
mtor,  D.rerio
mechanistic target of rapamycin (serine/threonine kinase)
NP_001070679.2
2515 aa
Tor,  D.melanogaster
Target of rapamycin
NP_001260427.1
2471 aa
AgaP_AGAP007873,  A.gambiae
AgaP_AGAP007873
XP_317619.4
2477 aa
TOR2,  S.cerevisiae
TOR2
NP_012719.2
2474 aa
KLLA0B13948g,  K.lactis
KLLA0B13948g
XP_452152.1
2450 aa
AGOS_AFR420W,  E.gossypii
AGOS_AFR420W
NP_985967.2
2462 aa
tor2,  S.pombe
tor2
NP_595359.2
2337 aa
MGG_15156,  M.oryzae
MGG_15156
XP_003710485.1
2460 aa
NCU05608,  N.crassa
NCU05608
XP_960570.1
2509 aa
TOR,  A.thaliana
TOR
NP_175425.2
2481 aa
Os05g0235300,  O.sativa
Os05g0235300
NP_001054988.2
1427 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Rapamycin_bind (pfam08771)
  Rapamycin binding domain.
FATC (pfam02260)
  FATC domain.
DUF3385 (pfam11865)
  Domain of unknown function (DUF3385).
HEAT_EZ (pfam13513)
  HEAT-like repeat.
FAT (pfam02259)
  FAT domain.
FAT (pfam02259)
  FAT domain.
FATC (pfam02260)
  FATC domain.
Rapamycin_bind (pfam08771)
  Rapamycin binding domain.
DUF3385 (pfam11865)
  Domain of unknown function (DUF3385).
PI3Kc_like (cl00119)
  Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...
HEAT_EZ (cl02500)
  The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mtor includes H.sapiens MTOR and R.norvegicus Mtor.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (22 transcripts, 12 species)
Actinopterygii - bony fishes (22 transcripts, 11 species)
Aves - birds (4 transcripts, 2 species)
Ascidiacea - tunicates (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (6 transcripts, 5 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)
Polychaeta - segmented worms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (41 transcripts, 26 species)
Liliopsida - monocots (13 transcripts, 9 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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