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HomoloGene:22614. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PDCD6IP,  H.sapiens
programmed cell death 6 interacting protein
NP_001155901.1
873 aa
PDCD6IP,  P.troglodytes
programmed cell death 6 interacting protein
XP_001169561.1
868 aa
PDCD6IP,  M.mulatta
programmed cell death 6 interacting protein
XP_002803107.1
859 aa
PDCD6IP,  C.lupus
programmed cell death 6 interacting protein
XP_005634263.1
874 aa
PDCD6IP,  B.taurus
programmed cell death 6 interacting protein
XP_005222647.1
880 aa
Pdcd6ip,  M.musculus
programmed cell death 6 interacting protein
NP_001158149.1
874 aa
Pdcd6ip,  R.norvegicus
programmed cell death 6 interacting protein
NP_001025081.2
868 aa
PDCD6IP,  G.gallus
programmed cell death 6 interacting protein
NP_001026164.1
882 aa
pdcd6ip,  X.tropicalis
programmed cell death 6 interacting protein
NP_001011064.1
870 aa
pdcd6ip,  D.rerio
programmed cell death 6 interacting protein
NP_998525.2
866 aa
ALiX,  D.melanogaster
ALG-2 interacting protein X
NP_651582.1
836 aa
AgaP_AGAP005531,  A.gambiae
AgaP_AGAP005531
XP_315531.3
862 aa
alx-1,  C.elegans
alx-1
NP_499213.1
861 aa
RIM20,  S.cerevisiae
RIM20
NP_014918.1
661 aa
KLLA0C07348g,  K.lactis
KLLA0C07348g
XP_452526.1
652 aa
AGOS_AER342C,  E.gossypii
AGOS_AER342C
NP_985198.1
631 aa
MGG_00833,  M.oryzae
MGG_00833
XP_003718148.1
849 aa
NCU05876,  N.crassa
NCU05876
XP_959867.1
886 aa
AT1G15130,  A.thaliana
AT1G15130
NP_172965.1
846 aa
Os10g0495300,  O.sativa
Os10g0495300
NP_001064950.2
923 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Activation of the retroviral budding factor ALIX.
Zhai Q, et al. J Virol 85, 9222-6 (2011).
The ESCRT complexes.
Hurley JH. Crit Rev Biochem Mol Biol 45, 463-87 (2010).
A crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments.
Pires R, et al. Structure 17, 843-56 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
V_Alix_like (cl14654)
  Protein-interacting V-domain of mammalian Alix and related domains.
Peptidase_M49 (pfam03571)
  Peptidase family M49.
MFMR (pfam07777)
  G-box binding protein MFMR.
DAZAP2 (pfam11029)
  DAZ associated protein 2 (DAZAP2).
Med25_NR-box (pfam11244)
  Mediator complex subunit 25 C-terminal NR box-containing.
YppG (pfam14179)
  YppG-like protein.
Pro-rich (pfam15240)
  Proline-rich.
BRO1_Alix_like (cl14649)
  Protein-interacting Bro1-like domain of mammalian Alix and related domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pdcd6ip includes H.sapiens PDCD6IP and R.norvegicus Pdcd6ip.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (22 transcripts, 14 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 11 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)
Polychaeta - segmented worms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (46 transcripts, 26 species)
Liliopsida - monocots (9 transcripts, 8 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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