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HomoloGene:31127. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SNAI2,  H.sapiens
snail family zinc finger 2
NP_003059.1
268 aa
SNAI2,  P.troglodytes
snail homolog 2 (Drosophila)
XP_003951309.1
268 aa
SNAI2,  M.mulatta
snail homolog 2 (Drosophila)
XP_001101435.1
268 aa
SNAI2,  C.lupus
snail homolog 2 (Drosophila)
NP_001091450.1
268 aa
SNAI2,  B.taurus
snail homolog 2 (Drosophila)
NP_001029710.1
268 aa
Snai2,  M.musculus
snail homolog 2 (Drosophila)
NP_035545.1
269 aa
Snai2,  R.norvegicus
snail family zinc finger 2
NP_037167.1
268 aa
SNAI2,  G.gallus
snail homolog 2 (Drosophila)
XP_419196.1
268 aa
snai2,  X.tropicalis
snail family zinc finger 2
NP_989424.1
266 aa
snai2,  D.rerio
snail homolog 2 (Drosophila)
NP_001008581.1
257 aa
K02D7.2,  C.elegans
K02D7.2
NP_499902.2
193 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Piebaldism.
Melanoma metastasis, modification of.
Waardenburg syndrome, type IID.



Publications
Articles associated with genes and sequences of this homology group.

SLUG silencing increases radiosensitivity of melanoma cells in vitro.
Arienti C, et al. Cell Oncol (Dordr) 36, 131-9 (2013).
Slug expression during melanoma progression.
Shirley SH, et al. Am J Pathol 180, 2479-89 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
COG5048 (COG5048)
  FOG: Zn-finger [General function prediction only].
zf-C2H2_6 (pfam13912)
  C2H2-type zinc finger.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Snai2 includes H.sapiens SNAI2 and R.norvegicus Snai2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 13 species)
Actinopterygii - bony fishes (13 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 3 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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