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HomoloGene:56489. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IGFBP5,  H.sapiens
insulin-like growth factor binding protein 5
NP_000590.1
272 aa
IGFBP5,  P.troglodytes
insulin-like growth factor binding protein 5
XP_003309513.1
272 aa
IGFBP5,  M.mulatta
insulin-like growth factor binding protein 5
XP_001087664.1
272 aa
IGFBP5,  C.lupus
insulin-like growth factor binding protein 5
XP_852885.1
271 aa
IGFBP5,  B.taurus
insulin-like growth factor binding protein 5
NP_001098797.1
271 aa
Igfbp5,  M.musculus
insulin-like growth factor binding protein 5
NP_034648.2
271 aa
Igfbp5,  R.norvegicus
insulin-like growth factor binding protein 5
NP_036949.1
271 aa
IGFBP5,  G.gallus
insulin-like growth factor binding protein 5
XP_422069.3
269 aa
igfbp5,  X.tropicalis
insulin-like growth factor binding protein 5
NP_001016042.1
204 aa
igfbp5a,  D.rerio
insulin-like growth factor binding protein 5a
NP_001119935.1
265 aa
igfbp5b,  D.rerio
insulin-like growth factor binding protein 5b
NP_001092224.1
268 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

IGFBP5 mediates high glucose-induced cardiac fibroblast activation.
Song SE, et al. J Mol Endocrinol 50, 291-303 (2013).
Effects of IGF-binding protein 5 in dysregulating the shape of human hair.
Sriwiriyanont P, et al. J Invest Dermatol 131, 320-8 (2011).
Insulin-like growth factor binding protein-5 influences pancreatic cancer cell growth.
Johnson SK & Haun RS. World J Gastroenterol 15, 3355-66 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TY (cl00150)
  Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases.
IGFBP (cl02472)
  Insulin-like growth factor binding protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Igfbp5 includes H.sapiens IGFBP5 and R.norvegicus Igfbp5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 13 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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