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HomoloGene:2593. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DEK,  H.sapiens
DEK oncogene
NP_003463.1
375 aa
DEK,  P.troglodytes
DEK oncogene
XP_003311080.1
374 aa
DEK,  M.mulatta
DEK oncogene
XP_001101463.1
375 aa
DEK,  C.lupus
DEK oncogene
XP_853159.2
426 aa
DEK,  B.taurus
DEK oncogene
NP_001093187.1
375 aa
Dek,  M.musculus
DEK oncogene (DNA binding)
NP_080176.2
380 aa
Dek,  R.norvegicus
DEK oncogene
NP_001004255.1
378 aa
DEK,  G.gallus
DEK oncogene
NP_001012578.1
369 aa
dek,  X.tropicalis
DEK oncogene
NP_001007866.1
388 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukemia, acute nonlymphocytic.



Publications
Articles associated with genes and sequences of this homology group.

Intercellular trafficking of the nuclear oncoprotein DEK.
Saha AK, et al. Proc Natl Acad Sci U S A 110, 6847-52 (2013).
DEK expression in Merkel cell carcinoma and small cell carcinoma.
Patel RM, et al. J Cutan Pathol 39, 753-7 (2012).
DEK expression in melanocytic lesions.
Kappes F, et al. Hum Pathol 42, 932-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DEK_C (pfam08766)
  DEK C terminal domain.
DEK_C (pfam08766)
  DEK C terminal domain.
SAP (cl02640)
  The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dek includes H.sapiens DEK and R.norvegicus Dek.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (7 transcripts, 5 species)
Eudicotyledons - eudicots (5 transcripts, 4 species)

 

 

 

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