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HomoloGene:1969. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CFP,  H.sapiens
complement factor properdin
NP_001138724.1
469 aa
CFP,  P.troglodytes
complement factor properdin
XP_001136665.1
469 aa
LOC707386,  M.mulatta
properdin-like
XP_002806283.1
429 aa
CFP,  C.lupus
complement factor properdin
XP_548978.2
464 aa
CFP,  B.taurus
complement factor properdin
NP_001069646.1
464 aa
Cfp,  M.musculus
complement factor properdin
NP_032849.2
464 aa
Cfp,  R.norvegicus
complement factor properdin
NP_001100227.1
465 aa
si:ch73-237c6.1,  D.rerio
si:ch73-237c6.1
NP_001107051.1
437 aa
cfp,  D.rerio
complement factor properdin
NP_001153598.1
437 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Properdin deficiency, X-linked.



Publications
Articles associated with genes and sequences of this homology group.

A new effector of lipid metabolism: complement factor properdin.
Gauvreau D, et al. Mol Immunol 51, 73-81 (2012).
A novel mutation W388X underlying properdin deficiency in a Finnish family.
Helminen M, et al. Scand J Immunol 75, 445-8 (2012).
Properdin in childhood and its association with wheezing and atopy.
Staley KG, et al. Pediatr Allergy Immunol 21, e787-91 (2010).
The role of properdin in murine zymosan-induced arthritis.
Dimitrova P, et al. Mol Immunol 47, 1458-66 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TSP_1 (pfam00090)
  Thrombospondin type 1 domain.
TSP_1 (cl15278)
  Thrombospondin type 1 domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cfp includes H.sapiens CFP and R.norvegicus Cfp.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (8 transcripts, 1 species)
Anthozoa - anthozoans (3 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (4 transcripts, 1 species)

Arthropoda
Maxillopoda - crustaceans (1 transcript, 1 species)

 

 

 

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