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HomoloGene:136. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GJA1,  H.sapiens
gap junction protein, alpha 1, 43kDa
NP_000156.1
382 aa
GJA1,  P.troglodytes
gap junction protein, alpha 1, 43kDa
XP_001164338.1
382 aa
GJA1,  M.mulatta
gap junction protein, alpha 1, 43kDa
XP_001109617.1
382 aa
GJA1,  C.lupus
gap junction protein, alpha 1, 43kDa
NP_001002951.2
382 aa
GJA1,  B.taurus
gap junction protein, alpha 1, 43kDa
NP_776493.1
383 aa
Gja1,  M.musculus
gap junction protein, alpha 1
NP_034418.1
382 aa
Gja1,  R.norvegicus
gap junction protein, alpha 1
NP_036699.1
382 aa
GJA1,  G.gallus
gap junction protein, alpha 1, 43kDa
NP_989917.1
381 aa
gja1,  X.tropicalis
gap junction protein, alpha 1, 43kDa
NP_988856.1
379 aa
cx43,  D.rerio
connexin 43
NP_571113.1
381 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Oculodentodigital dysplasia.
Syndactyly, type III.
Hypoplastic left heart syndrome.
Atrioventricular septal defect.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Connexin43 (pfam03508)
  Gap junction alpha-1 protein (Cx43).
Connexin (cl02435)
  Connexin.
Connexin_CCC (cl11207)
  Gap junction channel protein cysteine-rich domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gja1 includes H.sapiens GJA1 and R.norvegicus Gja1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 15 species)
Actinopterygii - bony fishes (12 transcripts, 8 species)
Aves - birds (3 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

 

 

 

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