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HomoloGene:4880. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GLO1,  H.sapiens
glyoxalase I
NP_006699.2
184 aa
GLO1,  P.troglodytes
glyoxalase I
XP_001173775.1
184 aa
GLO1,  M.mulatta
glyoxalase I
XP_001117098.1
184 aa
GLO1,  C.lupus
glyoxalase I
XP_532129.3
184 aa
GLO1,  B.taurus
glyoxalase I
NP_001076965.1
184 aa
LOC101905254,  B.taurus
lactoylglutathione lyase-like
XP_005208451.1
184 aa
Glo1,  M.musculus
glyoxalase 1
NP_079650.3
184 aa
Glo1,  R.norvegicus
glyoxalase 1
NP_997477.1
184 aa
GLO1,  G.gallus
glyoxalase I
XP_419481.1
180 aa
glo1,  X.tropicalis
glyoxalase 1
NP_001025545.1
184 aa
glo1,  D.rerio
glyoxalase 1
NP_998316.1
180 aa
CG1707,  D.melanogaster
CG1707
NP_610270.1
176 aa
AgaP_AGAP012072,  A.gambiae
AgaP_AGAP012072
XP_320454.4
178 aa
AgaP_AGAP012071,  A.gambiae
AgaP_AGAP012071
XP_320453.4
177 aa
GLO1,  S.cerevisiae
GLO1
NP_013710.1
326 aa
KLLA0F06226g,  K.lactis
KLLA0F06226g
XP_455362.1
338 aa
AGOS_ADR286C,  E.gossypii
AGOS_ADR286C
NP_984382.1
337 aa
glo1,  S.pombe
glo1
NP_596010.1
302 aa
MGG_11543,  M.oryzae
MGG_11543
XP_003718417.1
357 aa
NCU04815,  N.crassa
NCU04815
XP_960441.1
315 aa
AT1G08110,  A.thaliana
AT1G08110
NP_001030995.1
185 aa
Os05g0295800,  O.sativa
Os05g0295800
NP_001055113.1
189 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Autism, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

C332C genotype of glyoxalase 1 and its association with late diabetic complications.
Groener JB, et al. Exp Clin Endocrinol Diabetes 121, 436-9 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glo_EDI_BRP_like (cl14632)
  This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Glo1 includes H.sapiens GLO1 and R.norvegicus Glo1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 15 species)
Actinopterygii - bony fishes (15 transcripts, 10 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (37 transcripts, 32 species)
Liliopsida - monocots (9 transcripts, 9 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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