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HomoloGene:74300. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FER,  H.sapiens
fer (fps/fes related) tyrosine kinase
NP_005237.2
822 aa
FER,  P.troglodytes
fer (fps/fes related) tyrosine kinase
XP_001140014.1
822 aa
FER,  M.mulatta
fer (fps/fes related) tyrosine kinase
XP_001099988.1
808 aa
FER,  C.lupus
fer (fps/fes related) tyrosine kinase
NP_001003141.1
823 aa
FER,  B.taurus
fer (fps/fes related) tyrosine kinase
NP_001178265.1
822 aa
Fert2,  M.musculus
fer (fms/fps related) protein kinase, testis specific 2
NP_001033086.2
823 aa
Fert2,  R.norvegicus
fer (fms/fps related) protein kinase, testis specific 2
NP_001100398.1
453 aa
FER,  G.gallus
fer (fps/fes related) tyrosine kinase
XP_413981.2
822 aa
fer,  X.tropicalis
fer (fps/fes related) tyrosine kinase
NP_001016902.1
663 aa
fer,  D.rerio
fer (fps/fes related) tyrosine kinase
XP_693576.4
822 aa
Fps85D,  D.melanogaster
Fps oncogene analog
NP_001262411.1
871 aa
AgaP_AGAP003651,  A.gambiae
AgaP_AGAP003651
XP_003436548.1
783 aa
frk-1,  C.elegans
frk-1
NP_001255458.1
435 aa
kin-14,  C.elegans
kin-14
NP_492004.1
418 aa
T21G5.1,  C.elegans
T21G5.1
NP_491966.3
579 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Fer kinase regulates cell migration through α-dystroglycan glycosylation.
Yoneyama T, et al. Mol Biol Cell 23, 771-80 (2012).
Repression of Wnt signaling by a Fer-type nonreceptor tyrosine kinase.
Putzke AP & Rothman JH. Proc Natl Acad Sci U S A 107, 16154-9 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TyrKc (smart00219)
  Tyrosine kinase, catalytic domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Pkinase_Tyr (pfam07714)
  Protein tyrosine kinase.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
SH2 (cl15255)
  Src homology 2 (SH2) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fer includes H.sapiens FER.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 9 species)
Actinopterygii - bony fishes (15 transcripts, 8 species)
Amphibia - amphibians (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 9 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (5 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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