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HomoloGene:1842. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IRF4,  H.sapiens
interferon regulatory factor 4
NP_002451.2
451 aa
IRF4,  P.troglodytes
interferon regulatory factor 4
XP_518201.2
451 aa
IRF4,  C.lupus
interferon regulatory factor 4
XP_005640209.1
806 aa
IRF4,  B.taurus
interferon regulatory factor 4
NP_001193091.1
451 aa
Irf4,  M.musculus
interferon regulatory factor 4
NP_038702.1
450 aa
Irf4,  R.norvegicus
interferon regulatory factor 4
NP_001099578.1
450 aa
IRF4,  G.gallus
interferon regulatory factor 4
NP_989630.1
445 aa
irf4,  X.tropicalis
interferon regulatory factor 4
XP_002936464.1
443 aa
irf4a,  D.rerio
interferon regulatory factor 4a
NP_001116182.1
460 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Multiple myeloma.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IRF-3 (pfam10401)
  Interferon-regulatory factor 3.
IRF-3 (pfam10401)
  Interferon-regulatory factor 3.
IRF (cl00096)
  Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Irf4 includes H.sapiens IRF4 and R.norvegicus Irf4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (11 transcripts, 5 species)
Mammalia - mammals (9 transcripts, 9 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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