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HomoloGene:2794. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BECN1,  H.sapiens
beclin 1, autophagy related
NP_003757.1
450 aa
BECN1,  P.troglodytes
beclin 1, autophagy related
XP_511522.2
450 aa
BECN1,  M.mulatta
beclin 1, autophagy related
XP_001111787.1
450 aa
BECN1,  C.lupus
beclin 1, autophagy related
XP_005624499.1
471 aa
BECN1,  B.taurus
beclin 1, autophagy related
NP_001028799.1
448 aa
Becn1,  M.musculus
beclin 1, autophagy related
NP_062530.2
448 aa
Becn1,  R.norvegicus
beclin 1, autophagy related
NP_001029289.1
448 aa
BECN1,  G.gallus
beclin 1, autophagy related
NP_001006332.1
447 aa
becn1,  X.tropicalis
beclin 1, autophagy related
NP_001029112.1
445 aa
becn1,  D.rerio
beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)
NP_957166.1
447 aa
Atg6,  D.melanogaster
Autophagy-specific gene 6
NP_651209.1
422 aa
AgaP_AGAP003858,  A.gambiae
AgaP_AGAP003858
XP_310418.5
424 aa
bec-1,  C.elegans
bec-1
NP_500844.1
375 aa
VPS30,  S.cerevisiae
VPS30
NP_015205.1
557 aa
KLLA0F01166g,  K.lactis
KLLA0F01166g
XP_455132.1
461 aa
AGOS_ACR154W,  E.gossypii
AGOS_ACR154W
NP_983556.1
451 aa
atg6,  S.pombe
atg6
XP_001713051.1
464 aa
MGG_03694,  M.oryzae
MGG_03694
XP_003716187.1
503 aa
NCU03122,  N.crassa
NCU03122
XP_964981.2
454 aa
ATG6,  A.thaliana
ATG6
NP_567116.1
517 aa
Os03g0644000,  O.sativa
Os03g0644000
NP_001050756.1
501 aa
Os01g0681400,  O.sativa
Os01g0681400
NP_001043880.1
500 aa
Os03g0258500,  O.sativa
Os03g0258500
NP_001173355.1
543 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

[Research of the relationship of ubiquinone and beclin-1 and liver mitochondria].
Xie F, et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 27, 250-2 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MT (pfam12777)
  Microtubule-binding stalk of dynein motor.
APG6 (pfam04111)
  Autophagy protein Apg6.
APG6 (pfam04111)
  Autophagy protein Apg6.
BH3 (pfam15285)
  Beclin-1 BH3 domain, Bcl-2-interacting.
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.
DUF342 (cl19219)
  Protein of unknown function (DUF342).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Becn1 includes H.sapiens BECN1 and R.norvegicus Becn1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 15 species)
Actinopterygii - bony fishes (12 transcripts, 12 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 12 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (33 transcripts, 28 species)
Liliopsida - monocots (16 transcripts, 9 species)
Coniferopsida - conifers (4 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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