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HomoloGene:4147. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ST8SIA4,  H.sapiens
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_005659.1
359 aa
ST8SIA4,  P.troglodytes
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_001032379.1
359 aa
ST8SIA4,  M.mulatta
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
XP_001097339.1
359 aa
ST8SIA4,  C.lupus
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
XP_546003.3
359 aa
ST8SIA4,  B.taurus
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_001001163.1
359 aa
St8sia4,  M.musculus
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_033209.1
359 aa
St8sia4,  R.norvegicus
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_446366.1
454 aa
ST8SIA4,  G.gallus
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_989614.1
359 aa
st8sia4,  X.tropicalis
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_001090747.1
359 aa
st8sia4,  D.rerio
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NP_001092886.1
358 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Polysialic acid governs T-cell development by regulating progenitor access to the thymus.
Drake PM, et al. Proc Natl Acad Sci U S A 106, 11995-2000 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glyco_transf_29 (pfam00777)
  Glycosyltransferase family 29 (sialyltransferase).
Glyco_transf_29 (pfam00777)
  Glycosyltransferase family 29 (sialyltransferase).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus St8sia4 includes H.sapiens ST8SIA4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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